The Celebrex (celecoxib) Report
Information on bextra vs celebrex, side effects, drug dosage, concerns & medication questions

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Celebrex

Celebrex is part of a class of drugs call Non-steroidal anti-inflammatory drugs or NSAIDs. The active ingredient in Celebrex is celecoxib and works as a cyclooxygenase (COX)-2 specific inhibitor.

What medical conditions is Celebrex used to treat? Celebrex is a non-steroidal anti-inflammatory medicine (NSAID) that is used to reduce pain and inflammation (swelling and soreness). Celebrex is a medicine for:  relief of osteoarthritis (the arthritis caused by age-related “wear and tear” on bones and joints)  relief of rheumatoid arthritis in adults  management of acute pain in adults (like the short term pain you can get after a dental or surgical operation)  treatment of menstrual pain (pain during women’s monthly periods)  What is a Typical Celebrex Dosage? Typical Celebrex dosages are 100 mg BID and 200 mg BID

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Who should not take Celebrex? 

Do not take Celebrex if you: 

• have had an allergic-type reaction to sulfa medicines 
• have had asthma, hives or allergic-type reactions after taking aspirin or other NSAID medicines 
• are allergic to Celebrex or to any of the ingredients in Celebrex 

If you have asthma, you may have aspirin-sensitive asthma. If an aspirin-sensitive asthmatic takes aspirin it can cause severe narrowing of the airway (bronchospasm), and even death. Since this type of reaction to aspirin and other NSAID medicines have happened in aspirin-sensitive patients, aspirin-sensitive patients should not take Celebrex. 

Special Warnings with Celebrex

Celebrex and other NSAID medicines can cause stomach ulcers that bleed. The chance of this serious problem increases the longer you take Celebrex and with higher doses of Celebrex. Stomach bleeding can also happen suddenly while you take Celebrex. Stop taking Celebrex and call your healthcare provider right away if you get: 

• a burning stomach pain 
• black bowel movements that look like tar 
• vomit that looks like blood or coffee grounds 

Celebrex and other NSAID medicines can cause serious allergic reactions that include swelling of the face, lips, tongue or throat. These allergic reactions may cause problems with breathing, swallowing, and wheezing. Serious allergic skin reactions have also happened. 

General Precautions with Celebrex

Celebrex and other NSAID medicines can cause serious problems such as liver damage. Some of the warning signs of liver damage are nausea, vomiting, tiredness, loss of appetite, itching, yellow coloring of skin or eyes, “flu-like” symptoms and dark urine. If these happen, stop taking Celebrex and call your health care provider right away. 

Celebrex and other NSAID medicines can cause serious kidney problems that include sudden kidney failure or worsening of kidney problems that you already have. 

Celebrex and other NSAID medicines can cause fluid retention (holding of water in your body) and swelling. Fluid retention can be a serious problem if you have high blood pressure or heart failure. 

What are some possible side effects of Celebrex?

In addition to the serious side effects listed above, some common, but less serious side effects with Celebrex include: 

• headache 
• indigestion 
• upper respiratory tract infection (a "cold") 
• diarrhea 
• sinus inflammation 
• stomach pain 
• nausea 

Source: FDA Celebrex Patient Information Sheet